Sections.2-2.3: transcription and translation, transcriptional regulation. HW1 pplane8 (Needed for Problem 2) 2 7 Apr 9 Apr, mbe, circuit motifs, feed-forward loops enable temporal filtering and pulse generation Futile cycles generate zero-order ultrasensitivity (phospho-switches) Multi-gene positive feedback loops can enable toggle switch behaviors Positive feedback can generate hysteresis and irreversibility. Science signaling, 321(5885 126, 2008 A synthetic oscillatory network of transcriptional regulators, elowitz and leibler. A fast, robust and tunable synthetic gene oscillator, stricker,. Circadian control make of global gene expression by the cyanobacterial master regulator Rpaa, markson js,. Cell, 2013 Dec 5;155(6 1396-408. Ordered phosphorylation governs oscillation of a three-protein circadian clock. The molecular clockwork of a protein-based circadian oscillator.
Degradation rates control response times in simple open-loop gene regulation. Autoregulatory feedback loops modulate the response times of genetic circuits, limit variability, and can enable rate-responsive systems. Cooperative responses report can enable switch-like regulation and bistability. Circuit motifs can help identify functional modules in complex circuits. Recitation section: 4 Apr, bi 250b: Alon, Ch 1: Introduction, alon, Ch 2: Transcription networks : basic concepts. Alon, Ch 3: Autoregulation : a network motif. Be 150: bfs ch 1 : Introductory concepts (skim bfs ch 2 : Modeling of Core Processes, section.1: Modeling Techniques (skim).
Vipul Singhal (cns recitation: Fr 11-12, location ann107, this is the course homepage for be 150/Bi 250 for Spring 2014. This page contains all of the information about the material that will be covered in the class, as well as links to the homeworks and information about the course projects and grading. There is also a forum for students to ask questions, and can be accessed here. You will need to create a piazza account to enroll. There will be 2-3 one-hour lectures each week, as well as occasional one-hour tutorials, recitations or journal club. Week, date, topic, reading, homework 1 31 Mar 2 Apr, mBE/RMM. Course overview, gene circuit dynamics, introduction to the course, rate equations enable analysis of gene regulation circuits.
Phys 4267/6268 Introduction to nonlinear Dynamics and Chaos
Know the effect of poles and zeros, as well as associated system properties such as causality and bibo stability, on the existence and qualitative nature of steady-state behavior; Know how to use feedback to move system poles to desired locations to extract specified behaviors from. Coverage: van Lec, d, hw, q, e, oh student Success: Very good Know how to derive and exploit basic concepts in communication theory, including amplitude modulation and frequency modulation. Coverage: Lec, d, hw, q, e, oh student Success: Very good Understand how to use the unilateral Laplace or Z transform to decompose the response of an lti system into a zero-state component and a zero-input component. Solve linear, constant-coefficient differential or difference equations, with possibly non-zero initial conditions. Coverage: Lec, d, hw, q, e, oh student Success: Very good develop reasonably-accurate mathematical models for physical systems, find lti approximations to the models, produce block-diagram implementations of the mathematical models, and analyze the block diagram realizations with a view toward designing more complex systems. Coverage: Lec, d, hw, q, e, oh student Success: Very good learn to develop and analyze state-space models of linear and nonlinear systems.
This includes drawing qualitative plots of state trajectories; determining internal stability including the stability of equilibrium points; determining the modes of lti systems, especially second-order systems, by performing eigenanalysis of the state transition matrix; developing an aptitude for modeling a multidisciplinary array of systems. Coverage: Lec, d, hw, q, e, oh student Success: good topics covered: Signals and Systems Linearity, causality, bibo stability, time invariance, memory, invertibility linear Time-Invariant Systems Convolution integral and convolution summation Impulse response, frequency response differential equations, homogeneous and particular solutions Difference equations fourier Series. State-Space modeling and Analysis of Linear and Nonlinear Systems Prepared bio by: Babak ayazifar Date: 8 February 2009. Systems biology, instructors, michael Elowitz (Bi/BE/APh richard Murray (CDS/BE). Lectures: mwf 11-12, 200 brd, teaching Assistants, victoria hsiao (BE).
Know how to draw the frequency-domain magnitude and phase plots using geometric reasoning. Coverage: Lec, d, hw, q, e, oh student Success: Excellent Understand the sampling theorem and how it links continuous-time signals to discrete-time signals. In particular, know how to derive the sampling theorem from first principles—from the basic properties of the fourier transform; how the spectrum of a sampled signal relates to the spectrum of the original signal; how to use the sampling theorem to understand aliasing phenomena. Coverage: Lec, d, hw, q, e, oh student Success: Very good Understand the need to define two new transforms—the laplace and Z transforms—to treat a class of signals broader than what the fourier transform can handle. Coverage: Lec, d, hw, q, e, oh student Success: Excellent Understand the combined implications of linearity and time invariance in the laplace and Z transform domains. In particular, know how to represent the response of an lti system to a more general form of complex exponential— e st in continuous time or z n in discrete-time—and understand that complex exponentials are eigenfunctions of lti systems; use the laplace transform to determine.
Understand the implications of causality, bibo stability, invertibility and other system properties on the region of convergence of the transform. Understand the relationship between the locations of the poles and zeros with system properties such as causality, bibo stability, invertibility, and frequency response. Determine the input-output behavior of an lti system entirely in the transform domain, using relationships between time-domain and the frequency-domain (e.g., convolution in the time domain corresponds to multiplication in the frequency domain understand the conditions under which the transfer function of a system (or. Coverage: Lec, d, hw, q, e, oh student Success: Excellent Understand the relationships among the various representations of lti systems—linear constant-coefficient difference or differential equation, frequency response, transfer function, and impulse response—and infer one representation from another (e.g., determine the impulse response from the difference. Evaluate the z transform on the unit circle for discrete-time functions; Infer the properties of the fourier transform magnitude and phase plots from the locations of the poles and zeros; Design low-pass, band-pass, high-pass, notch, anti-notch, and all-pass filters by appropriate distribution of poles and. Coverage: Lec, d, hw, q, e, oh student Success: Excellent Understand the various properties of the four fourier transforms, the laplace transform, and the z transform—including time-shift, modulation (frequency shift duality, symmetry and anti-symmetry—and exploit them to analyze and design signals and systems. Coverage: Lec, d, hw, q, e, oh student Success: Very good. Understand the properties, as well the analysis and design implications, of interconnections of lti systems—parallel, series (cascade and feedback—in the time and transform domains.
Steven h strogatz solutions
Coverage: Lec, d, hw, q, e, oh student Success: Excellent Know the principles of vector spaces, including how to relate the concepts of basis, dimension, inner product, and norm to signals. Coverage: Lec, d, hw, q, e, oh student Success: Very good learn to treat signals as vectors in best a vector space and ascribe geometry to that space by defining an appropriate inner product—in both discrete-time and continuous-time, and for both periodic and aperiodic signals. For example, treat the set of periodic discrete-time signals having period p as a vector space, and define an inner product for that space. Coverage: Lec, d, hw, q, e, oh student Success: Excellent Know how to analyze, design, approximate, and manipulate signals using vector-space concepts. For example, know how to project a signal onto another signal, and exploit signal orthogonality to develop fourier series expansions of periodic discrete-time and continuous-time signals—that is, decompose a signal in terms of complex exponentials in the frequency domain; know how to interpret and plot. Understand that a signals energy is the 2-norm of a signal, that the 2-norm is defined according to an appropriate inner product, and that signal energy can be expressed in the time and frequency domains via parsevals relation. Coverage: Lec, d, hw, q, e, oh student Success: Very good Determine fourier transforms for continuous-time and discrete-time signals (or impulse-response functions and understand how to interpret and plot fourier transform magnitude and phase functions. Understand the discontinuous nature of the fourier transform of a signal that is not absolutely summable or integrable. Understand the impulsive nature of the fourier transform of a periodic signal, and how the fourier series coefficients relate to the fourier transform of the signal.
The various components of the course encourage students to think graphically and to draw, before they reach for mathematical formulae. Lectures, discussion sections, and instructors office hours promote group work by engaging the students in a collaborative learning environment where they divide into groups of 3-5 students and discuss the solutions to various problems. In discussion sections and office hours, students present their solutions to their peers on the board; they generate peer discussion by asking each other questions and assisting each other toward solutions. Recognizing that team work is an integral part of engineering practice, the homework policy encourages collaborative groups of up to five students. Lectures also cultivate group learning. For almost every example problem the students encounter in lecture, they take time to discuss the solution among themselves, explaining concepts and learning about alternative solutions from their peers. Course learning Objectives and Outcomes: This course trains students for an intermediate level of fluency with signals and systems in both continuous time and discrete time, in preparation for more advanced subjects in digital signal processing (including audio, image and video processing communication theory, and. Upon successful completion, a student should: Classify systems based on their properties: in particular, understand and exploit the implications of linearity, time-invariance, causality, memory, and bounded-input, bounded-out (bibo) stability.
outcomes: (a (b (c (e (g (i (k). Ee 120 continues the tradition of its lower-division prerequisite course ee 20N by requiring students to apply a fundamental knowledge of mathematics, science and engineering to not only solve electrical and computer engineering problems, but also to recognize the multidisciplinary reach of the topics and. Students learn modern skills, techniques and engineering tools. They refine their skills in back-of-the-envelope and design-oriented analysis. They learn to model signals and systems, with an eye toward design. Problem sets and exams are designed to probe a thorough understanding of fundamental concepts and to de-emphasize rote algebraic manipulation. Exam problems insist on refined and to-the-point responses; limited space is allocated for each problem to encourage students to think more clearly and logically, and to articulate their responses efficiently and without clutter.
Review of: Appendix A (sets and functions appendix B (complex numbers chapter 1 (Signals and Systems). Chapter 2 (Defining Signals and Systems). Extended coverage of: Chapter 7 (Frequency domain chapter 8 (Frequency response chapter 9 (Filtering). Chapter 10 (The four interests fourier Transforms). In-depth first-time coverage of: Chapter 11 (Sampling and Reconstruction chapter 12 (Stability chapter 13 (Laplace and z transforms). Chapter 14 (Composition and feedback control). Miscellaneous: Chapter 5 (Linear Systems/State-Space Analysis recommended:. Nawab, signals and Systems, prentice-hall, 1997.
Chapter.1 Solutions nonlinear Dynamics And Chaos 2nd
EE 120: desk Signals and Systems, department: Electrical Engineering and Computer Sciences, instructor:. Babak ayazifar (eecs faculty). Credit Units: 4, prerequisites: ee 20N (Introductory signals and Systems). Math 53 (Multivariate calculus math 54 (Linear Algebra and Differential Equations). Course Structure: Lecture hours per week (Lec. Discussion (recitation) section hours per week (D 1 (not mandatory). Instructor office hours, focused on group- based problem solving (oh 2 (not mandatory). Course components: Problem Sets/Homework (hw pop quizzes (q exams (E). Varaiya, structure and Interpretation of Signals and Systems, Addison-Wesley, 2003.